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Last updated: 2014/10/27

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C2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000717-T03
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-C2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 83.3
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-C2 antibody (H00000717-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000717-T03
    C2 transfected lysate.
    Western Blot
    QC Testing of H00000717-T03
    Lane 1: C2 transfected lysate ( 83.30 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 717
  • Gene Name:
  • C2
  • Gene Alias:
  • CO2,DKFZp779M0311
  • Gene Description:
  • complement component 2
  • Gene Summary:
  • Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined
  • Other Designations:
  • C3/C5 convertase,OTTHUMP00000029277,OTTHUMP00000062690,complement C2,complement component C2
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