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BMPR2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000659-T02
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-BMPR2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 115.2
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-BMPR2 antibody (H00000659-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000659-T02
    BMPR2 transfected lysate.
    Western Blot
    QC Testing of H00000659-T02
    Lane 1: BMPR2 transfected lysate ( 115.20 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 659
  • Gene Name:
  • BMPR2
  • Gene Alias:
  • BMPR-II,BMPR3,BMR2,BRK-3,FLJ41585,FLJ76945,PPH1,T-ALK
  • Gene Description:
  • bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Gene Summary:
  • This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq
  • Other Designations:
  • BMP type II receptor,bone morphogenetic protein receptor type II,bone morphogenetic protein receptor type-2,primary pulmonary hypertension 1,serine/threonine kinase,type II activin receptor-like kinase,type II receptor for bone morphogenetic protein-4
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