BMPR1B 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
BMPR1B transfected lysate.
Western Blot
Lane 1: BMPR1B transfected lysate ( 55.33 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BMPR1B full-length
Host
Human
Theoretical MW (kDa)
55.33
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BMPR1B antibody (H00000658-B01) by Western Blots.
SDS-PAGE Gel
BMPR1B transfected lysate.
Western Blot
Lane 1: BMPR1B transfected lysate ( 55.33 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BMPR1B
Entrez GeneID
658GeneBank Accession#
NM_001203.1Protein Accession#
NP_001194.1Gene Name
BMPR1B
Gene Alias
ALK-6, ALK6, CDw293
Gene Description
bone morphogenetic protein receptor, type IB
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. [provided by RefSeq
Other Designations
OTTHUMP00000161622|activin receptor-like kinase 6|serine/threonine receptor kinase
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Interactome
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