BMP5 (Human) Recombinant Protein (Q03)
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More Files
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Specification
Product Description
Human BMP5 partial ORF ( NP_066551.1, 323 a.a. - 454 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NQNRNKSSSHQDSSRMSSVGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGCH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
40.15
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — BMP5
Entrez GeneID
653GeneBank Accession#
NM_021073.1Protein Accession#
NP_066551.1Gene Name
BMP5
Gene Alias
MGC34244
Gene Description
bone morphogenetic protein 5
Omim ID
112265Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq
Other Designations
OTTHUMP00000016650
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Interactome
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Pathway
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Disease
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