PRDM1 monoclonal antibody (M10), clone 1G9
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More Files
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Western Blot (Tissue lysate)
PRDM1 monoclonal antibody (M10), clone 1G9. Western Blot analysis of PRDM1 expression in human spleen.
Immunofluorescence
Immunofluorescence of monoclonal antibody to PRDM1 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (33.66 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant PRDM1.
Immunogen
PRDM1 (NP_001189, 422 a.a. ~ 493 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HPMLNPTSLPSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHV
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.66 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PRDM1 monoclonal antibody (M10), clone 1G9. Western Blot analysis of PRDM1 expression in human spleen.Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to PRDM1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — PRDM1
Entrez GeneID
639GeneBank Accession#
NM_001198Protein Accession#
NP_001189Gene Name
PRDM1
Gene Alias
BLIMP1, MGC118922, MGC118923, MGC118924, MGC118925, PRDI-BF1
Gene Description
PR domain containing 1, with ZNF domain
Omim ID
603423Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq
Other Designations
B-lymphocyte-induced maturation protein 1|OTTHUMP00000016918|PR-domain zinc finger protein 1|PRDI-binding factor-1|beta-interferon gene positive-regulatory domain I binding factor|positive regulatory domain I-binding factor 1
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Interactome
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Disease
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