BCL3 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of BCL3 transfected lysate using rabbit polyclonal anti-BCL3 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-BCL3.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of BCL3 transfected lysate using rabbit polyclonal anti-BCL3 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-BCL3.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-BCL3 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-BCL3 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — BCL3
Entrez GeneID
602Gene Name
BCL3
Gene Alias
BCL4, D19S37
Gene Description
B-cell CLL/lymphoma 3
Omim ID
109560Gene Ontology
HyperlinkGene Summary
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq
Other Designations
B-cell leukemia/lymphoma 3|B-cell lymphoma 3-encoded protein|chronic lymphatic leukemia protein
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Interactome
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Disease
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Publication Reference
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Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation.
Gringhuis SI, Kaptein TM, Wevers BA, Mesman AW, Geijtenbeek TB.
Nature Communications 2014 May; 5:3898.
Application：IP-WB, Human, Dendritic cells.
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Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation.
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