BCL2L1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
BCL2L1 MaxPab rabbit polyclonal antibody. Western Blot analysis of BCL2L1 expression in human spleen.
Western Blot (Cell lysate)
BCL2L1 MaxPab rabbit polyclonal antibody. Western Blot analysis of BCL2L1 expression in A-431.
Western Blot (Transfected lysate)
Western Blot analysis of BCL2L1 expression in transfected 293T cell line (H00000598-T01) by BCL2L1 MaxPab polyclonal antibody.
Lane 1: BCL2L1 transfected lysate(26.00 KDa).
Lane 2: Non-transfected lysate.
In situ Proximity Ligation Assay (Cell)
Proximity Ligation Analysis of protein-protein interactions between BCL2L1 and BAX. HeLa cells were stained with anti-BCL2L1 rabbit purified polyclonal 1:1200 and anti-BAX mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to BCL2L1 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human BCL2L1 protein.
Immunogen
BCL2L1 (NP_612815.1, 1 a.a. ~ 233 a.a) full-length human protein.
Sequence
MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
BCL2L1 MaxPab rabbit polyclonal antibody. Western Blot analysis of BCL2L1 expression in human spleen.Western Blot (Cell lysate)
BCL2L1 MaxPab rabbit polyclonal antibody. Western Blot analysis of BCL2L1 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of BCL2L1 expression in transfected 293T cell line (H00000598-T01) by BCL2L1 MaxPab polyclonal antibody.
Lane 1: BCL2L1 transfected lysate(26.00 KDa).
Lane 2: Non-transfected lysate.
In situ Proximity Ligation Assay (Cell)
Proximity Ligation Analysis of protein-protein interactions between BCL2L1 and BAX. HeLa cells were stained with anti-BCL2L1 rabbit purified polyclonal 1:1200 and anti-BAX mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to BCL2L1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — BCL2L1
Entrez GeneID
598GeneBank Accession#
NM_138578Protein Accession#
NP_612815.1Gene Name
BCL2L1
Gene Alias
BCL-XL/S, BCL2L, BCLX, Bcl-X, DKFZp781P2092, bcl-xL, bcl-xS
Gene Description
BCL2-like 1
Omim ID
600039Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq
Other Designations
OTTHUMP00000030550|OTTHUMP00000030551|OTTHUMP00000030553
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Interactome
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Pathway
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Disease
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