ATP4B (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human ATP4B partial ORF ( NP_000696.1, 67 a.a. - 176 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGYSPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ATP4B
Entrez GeneID
496GeneBank Accession#
NM_000705Protein Accession#
NP_000696.1Gene Name
ATP4B
Gene Alias
ATP6B
Gene Description
ATPase, H+/K+ exchanging, beta polypeptide
Omim ID
137217Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq
Other Designations
ATPase, H+/K+ transporting, beta polypeptide|gastric H+/K+ ATPase beta subunit|gastric hydrogen-potassium ATPase, beta|hydrogen/potassium-exchanging ATPase 4B|potassium-transporting ATPase beta chain|proton pump beta chain
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Interactome
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Pathway
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Disease
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