ATP1B2 monoclonal antibody (M04), clone 4E3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ATP1B2.
Immunogen
ATP1B2 (NP_001669.3, 84 a.a. ~ 193 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIKMNRVINFYAGAN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ATP1B2 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — ATP1B2
Entrez GeneID
482GeneBank Accession#
NM_001678Protein Accession#
NP_001669.3Gene Name
ATP1B2
Gene Alias
AMOG
Gene Description
ATPase, Na+/K+ transporting, beta 2 polypeptide
Omim ID
182331Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. [provided by RefSeq
Other Designations
Na+/K+ -ATPase beta 2 subunit|Na, K-ATPase beta-2 polypeptide|adhesion molecule on glia|sodium/potassium-dependent ATPase beta-2 subunit|sodium/potassium-transporting ATPase beta-2 chain
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Interactome
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Pathway
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Disease
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