ABCC6 monoclonal antibody (M02), clone 5D8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ABCC6.
Immunogen
ABCC6 (NP_001162, 831 a.a. ~ 930 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IAEMGSYQELLQRKGALVCLLDQARQPGDRGEGETEPGTSTKDPRGTSAGRRPELRRERSIKSVPEKDRTTSEAQTEVPLDDPDRAGWPAGKDSIQYGRV
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ABCC6 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — ABCC6
Entrez GeneID
368GeneBank Accession#
NM_001171Protein Accession#
NP_001162Gene Name
ABCC6
Gene Alias
ABC34, ARA, EST349056, MLP1, MOATE, MRP6, PXE, PXE1
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family C, member 6|anthracycline resistance-associated
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Interactome
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Pathway
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Disease
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