Immunoprecipitation of XIAP transfected lysate using anti-XIAP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with BIRC4 purified MaxPab mouse polyclonal antibody (B01P) (H00000331-B01P).
The protein encoded by this gene is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. This protein inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. It also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. [provided by RefSeq
Other Designations:
OTTHUMP00000023975,OTTHUMP00000196392,apoptosis inhibitor 3,baculoviral IAP repeat-containing 4,baculoviral IAP repeat-containing protein 4