BIRC3 purified MaxPab mouse polyclonal antibody (B01P)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human BIRC3 protein.
Immunogen
BIRC3 (NP_001156.1, 1 a.a. ~ 604 a.a) full-length human protein.
Sequence
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWPLTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRTFLS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of BIRC3 expression in transfected 293T cell line (H00000330-T01) by BIRC3 MaxPab polyclonal antibody.
Lane 1: BIRC3 transfected lysate(66.44 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — BIRC3
Entrez GeneID
330GeneBank Accession#
NM_001165.3Protein Accession#
NP_001156.1Gene Name
BIRC3
Gene Alias
AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49
Gene Description
baculoviral IAP repeat-containing 3
Omim ID
601721Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq
Other Designations
TNFR2-TRAF signaling complex protein|apoptosis inhibitor 2|baculoviral IAP repeat-containing protein 3|inhibitor of apoptosis protein 1|mammalian IAP homolog C
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Interactomes
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Pathways
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Diseases
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