ANXA1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ANXA1 protein.
Immunogen
ANXA1 (NP_000691.1, 1 a.a. ~ 346 a.a) full-length human protein.
Sequence
MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ANXA1 MaxPab polyclonal antibody. Western Blot analysis of ANXA1 expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of ANXA1 expression in transfected 293T cell line (H00000301-T01) by ANXA1 MaxPab polyclonal antibody.
Lane 1: ANXA1 transfected lysate(38.06 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to ANXA1 on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 3 ug/ml]Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ANXA1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ANXA1
Entrez GeneID
301GeneBank Accession#
NM_000700Protein Accession#
NP_000691.1Gene Name
ANXA1
Gene Alias
ANX1, LPC1
Gene Description
annexin A1
Omim ID
151690Gene Ontology
HyperlinkGene Summary
Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity. [provided by RefSeq
Other Designations
OTTHUMP00000021474|OTTHUMP00000021475|annexin I|annexin I (lipocortin I)|lipocortin I
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Interactome
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Disease
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Publication Reference
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VR09 Cell Line: An EBV-Positive Lymphoblastoid Cell Line with In Vivo Characteristics of Diffuse Large B Cell Lymphoma of Activated B-Cell Type.
Nichele I, Zamo A, Bertolaso A, Bifari F, Tinelli M, Franchini M, Stradoni R, Aprili F, Pizzolo G, Krampera M.
PLoS One 2012 Dec; 7(12):e52811.
Application:IHC, Human, Mouse, Human VR09 cell, Mouse tumor masses.
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Absence of TCL1A expression is a useful diagnostic feature in splenic marginal zone lymphoma.
Munari E, Rinaldi M, Ambrosetti A, Bonifacio M, Bonalumi A, Chilosi M, Zamò A.
Virchows Archiv: an International Journal of Pathology 2012 Dec; 461(6):677.
Application:IHC, Human, Human bone marrow samples, Human spleens.
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VR09 Cell Line: An EBV-Positive Lymphoblastoid Cell Line with In Vivo Characteristics of Diffuse Large B Cell Lymphoma of Activated B-Cell Type.
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