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> ALOX12B polyclonal antibody (A01)
ALOX12B polyclonal antibody (A01)
Catalog # : H00000242-A01
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Specification
Gene Info
Pathway
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Specification
Product Description:
Mouse polyclonal antibody raised against a partial recombinant ALOX12B.
Immunogen:
ALOX12B (NP_001130, 171 a.a. ~ 261 a.a) partial recombinant protein with GST tag.
Sequence:
NPNRPEWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIRKIFPGKKSVVSEYVAEHWAED
Host:
Mouse
Reactivity:
Human
Quality Control Testing:
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.12 KDa) .
Storage Buffer:
50 % glycerol
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
MSDS:
Download
Publication Reference
1.
A role for 12r-lipoxygenase in muc5ac expression by respiratory epithelial cells.
Garcia-Verdugo I, Benmohamed F, Tattermusch S, Leduc D, Charpigny G, Chignard M, Ollero M, Touqui L.Eur Respir J. 2012 Mar 22. [Epub ahead of print]
2.
Hepoxilin A(3) (HXA(3)) synthase deficiency is causative of a novel ichthyosis form.
Nigam S, Zafiriou MP, Deva R, Kerstin N, Geilen C, Ciccoli R, Sczepanski M, Lohse M.FEBS Lett. 2008 Jan 23;582(2):279-85. Epub 2007 Dec 18.
Applications
Western Blot (Cell lysate)
ALOX12B polyclonal antibody (A01), Lot # 051130JC01 Western Blot analysis of ALOX12B expression in Jurkat ( Cat # L017V1 ).
Protocol Download
Western Blot (Recombinant protein)
Protocol Download
ELISA
Application Image
Western Blot (Cell lysate)
enlarge
Western Blot (Recombinant protein)
ELISA
Gene Information
Entrez GeneID:
242
GeneBank Accession#:
NM_001139
Protein Accession#:
NP_001130
Gene Name:
ALOX12B
Gene Alias:
12R-LOX
Gene Description:
arachidonate 12-lipoxygenase, 12R type
Omim ID:
242100
,
603741
Gene Ontology:
Hyperlink
Gene Summary:
This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma. [provided by RefSeq
Other Designations:
epidermis-type lipoxygenase 12
Gene Pathway
Arachidonic acid metabolism
Metabolic pathways
Related Disease
Birth Weight
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Breast cancer
Breast Neoplasms
Cardiovascular Diseases
Coronary Disease
Genetic Predisposition to Disease
Glioblastoma
Glioma
Ichthyosiform Erythroderma, Congenital
Leukemia
Leukemia, Myeloid, Acute
Meningeal Neoplasms
Meningioma
Myocardial Infarction
Neoplasms, Glandular and Epithelial
Ovarian cancer
Ovarian Neoplasms
Stroke
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