ALDH3A1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ALDH3A1 full-length
Host
Human
Theoretical MW (kDa)
49.94
Interspecies Antigen Sequence
Mouse (81); Rat (82)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ALDH3A1 antibody (H00000218-B01) by Western Blots.
SDS-PAGE Gel
ALDH3A1 transfected lysate.
Western Blot
Lane 1: ALDH3A1 transfected lysate ( 49.94 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ALDH3A1
Entrez GeneID
218GeneBank Accession#
BC008892.2Protein Accession#
AAH08892.1Gene Name
ALDH3A1
Gene Alias
ALDH3, ALDHIII, MGC10406
Gene Description
aldehyde dehydrogenase 3 family, memberA1
Omim ID
100660Gene Ontology
HyperlinkGene Summary
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
aldehyde dehydrogenase 3A1|aldehyde dehydrogenase isozyme 3|aldehyde dehydrogenase type III|aldehyde dehydrogenase, dimeric NADP-preferring|stomach aldehyde dehydrogenase
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Interactome
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Pathway
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Disease
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