ADH5 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ADH5.
Immunogen
ADH5 (NP_000662, 82 a.a. ~ 165 a.a) partial recombinant protein with GST tag.
Sequence
KLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (96)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.35 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ADH5 polyclonal antibody (A01), Lot # DUM6060320QCS1. Western Blot analysis of ADH5 expression in human ovarian cancer.Western Blot (Recombinant protein)
ELISA
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Gene Info — ADH5
Entrez GeneID
128GeneBank Accession#
NM_000671Protein Accession#
NP_000662Gene Name
ADH5
Gene Alias
ADH-3, ADHX, FDH, GSNOR
Gene Description
alcohol dehydrogenase 5 (class III), chi polypeptide
Omim ID
103710Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq
Other Designations
alcohol dehydrogenase (class III), chi polypeptide|class III alcohol dehydrogenase 5|formaldehyde dehydrogenase|glutathione-dependent formaldehyde dehydrogenase
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Interactome
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Pathway
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Disease
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