ADA monoclonal antibody (M01), clone 4G4-1C6
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant ADA.
Immunogen
ADA (AAH40226.1, 1 a.a. ~ 363 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAIDLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (86)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (65.45 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ADA monoclonal antibody (M01), clone 4G4-1C6. Western Blot analysis of ADA expression in HL-60 ( Cat # L014V1 ).Western Blot (Cell lysate)
ADA monoclonal antibody (M01), clone 4G4-1C6. Western Blot analysis of ADA expression in Jurkat ( Cat # L017V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADA is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — ADA
Entrez GeneID
100GeneBank Accession#
BC040226Protein Accession#
AAH40226.1Gene Name
ADA
Gene Alias
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Gene Description
adenosine deaminase
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq
Other Designations
adenosine aminohydrolase
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Interactome
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Pathway
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Disease
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