GINS3/CEN16q FISH Probe
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human lung squamous cell carcinoma (FFPE) stained with GINS3/CEN16q FISH Probe. Human lung squamous cell carcinoma showed GINS3 gene amplification.
Hybridization position of the probes on the chromosome:
Hybridization position of the probes on the chromosome:
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: GINS3
Size: Approximately 370kb
Fluorophore: Texas Red
Location: 16q21Probe 2
Name: CEN16q
Size: Approximately 700kb
Fluorophore: FITC
Location: 16q12.1Probe Gap
The gap between two probes is approximately 8,660 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human lung squamous cell carcinoma (FFPE) stained with GINS3/CEN16q FISH Probe. Human lung squamous cell carcinoma showed GINS3 gene amplification. -
Gene Info — GINS3
Entrez GeneID
64785Gene Name
GINS3
Gene Alias
FLJ13912, PSF3
Gene Description
GINS complex subunit 3 (Psf3 homolog)
Omim ID
610610Gene Ontology
HyperlinkGene Summary
This gene encodes a protein subunit of the GINS heterotetrameric complex, which is essential for the initiation of DNA replication and replisome progression in eukaryotes. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
GINS complex subunit 3
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Interactome
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Disease
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