CKS1B/CEN1p FISH Probe
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: CKS1B
Size: Approximately 170kb
Fluorophore: Texas Red
Location: 1q21Probe 2
Name: CEN1p
Size: Approximately 780kb
Fluorophore: FITC
Location: 1p13.3Probe Gap
The gap between two probes is approximately 44,200 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — CKS1B
Entrez GeneID
1163Gene Name
CKS1B
Gene Alias
CKS1, PNAS-16, PNAS-18, ckshs1
Gene Description
CDC28 protein kinase regulatory subunit 1B
Omim ID
116900Gene Ontology
HyperlinkGene Summary
CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq
Other Designations
CDC2-associated protein CKS1|CDC28 protein kinase 1|CDC28 protein kinase 1B|NB4 apoptosis/differentiation related protein|OTTHUMP00000035541|PNAS-143|cell division control protein CKS1|cyclin-dependent kinases regulatory subunit 1
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Interactome
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Disease
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