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Last updated: 2014/7/28
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APBB1(Phospho S175) & APBB1 Protein Phosphorylation Antibody Pair

  • Catalog # : DP0056
  • Visit Frequency :
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  • Specification
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Dual recognition immunofluorescence result.

    QC Testing of DP0056
    Representative image of Proximity Ligation Assay of protein phosphorylation. HeLa cells were stained with dual recognition antibody pair set, rabbit polyclonal antibody 1:1200 and mouse purified polyclonal antibody 1:50. Each red dot represents one single phosphorylated protein. The images were analyzed using an optimized freeware (BlobFinder) download from The Centre for Image Analysis at Uppsala University.
  • Supplied Product:
  • Antibody pair set content:
    1. Phospho-APBB1 S175 rabbit polyclonal antibody (20 ul)
    With 0.09% sodium azide.
    2. APBB1 mouse purified polyclonal antibody (40 ug)
    In 1x PBS, pH 7.2
    *Reagents are sufficient for at least 30-50 assays using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Publication Reference
  • Applications
  • In situ Proximity Ligation Assay (Cell)
  • Application Image
  • In situ Proximity Ligation Assay (Cell)
  • Gene Information
  • Entrez GeneID:
  • 322
  • Gene Name:
  • APBB1
  • Gene Alias:
  • FE65,MGC:9072,RIR
  • Gene Description:
  • amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • Gene Summary:
  • The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known. [provided by RefSeq
  • Other Designations:
  • adaptor protein FE65a2,amyloid beta A4 precursor protein-binding, family B, member 1,stat-like protein
  • Gene Pathway
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