DUSP13 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human DUSP13 full-length ORF ( AAH09778, 1 a.a. - 198 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
47.52
Interspecies Antigen Sequence
Mouse (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Phosphatase Assay (Cdc25)
Phosphatase Assay (PTP)
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DUSP13
Entrez GeneID
51207GeneBank Accession#
BC009778Protein Accession#
AAH09778Gene Name
DUSP13
Gene Alias
BEDP, DUSP13A, DUSP13B, FLJ32450, MDSP, SKRP4, TMDP
Gene Description
dual specificity phosphatase 13
Gene Ontology
HyperlinkGene Summary
Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq
Other Designations
OTTHUMP00000019875|OTTHUMP00000060197|branching-enzyme interacting dual-specificity protein phosphatase|dual-specificity phosphatase SKRP4|muscle-restricted dual specificity phosphatase
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Interactome
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Disease
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