FREQ (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human FREQ full-length ORF ( AAH04856, 1 a.a. - 190 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.64
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FREQ
Entrez GeneID
23413GeneBank Accession#
BC004856Protein Accession#
AAH04856Gene Name
FREQ
Gene Alias
DKFZp761L1223, FLUP, NCS-1, NCS1
Gene Description
frequenin homolog (Drosophila)
Omim ID
603315Gene Ontology
HyperlinkGene Summary
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022356|frequenin homolog|frequenin-like ubiquitous protein|neuronal calcium sensor 1
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Interactome
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Disease
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