EXOSC8 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human EXOSC8 full-length ORF ( AAH20773, 1 a.a. - 276 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
56.1
Interspecies Antigen Sequence
Mouse (90); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — EXOSC8
Entrez GeneID
11340GeneBank Accession#
BC020773Protein Accession#
AAH20773Gene Name
EXOSC8
Gene Alias
CIP3, EAP2, OIP2, RP11-421P11.3, RRP43, Rrp43p, bA421P11.3, p9
Gene Description
exosome component 8
Omim ID
606019Gene Ontology
HyperlinkGene Summary
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq
Other Designations
CBP-interacting protein 3|OTTHUMP00000042274|Opa interacting protein 2|Opa-interacting protein 2
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Interactome
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Pathway
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