POLR2C (Human) Recombinant Protein (P02)
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Specification
Product Description
Human POLR2C full-length ORF ( AAH00409, 1 a.a. - 275 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
55.99
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — POLR2C
Entrez GeneID
5432GeneBank Accession#
BC000409Protein Accession#
AAH00409Gene Name
POLR2C
Gene Alias
RPB3, RPB31, hRPB33, hsRPB3
Gene Description
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Omim ID
180663Gene Ontology
HyperlinkGene Summary
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq
Other Designations
DNA directed RNA polymerase II polypeptide C|RNA polymerase II subunit 3|polymerase (RNA) II (DNA directed) polypeptide C (33kD)
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