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Last updated: 2016/10/23
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CytoBot™ - Circulating Rare Cell Negative Enrichment & Retrieval Automation

Three major subtypes of circulating rare cells in clinical applications are circulating tumor cells (CTCs), circulating progenitor cells (CPCs), and circulating fetal cells (CFCs). Abnova’s CytoBot™ is a revolutionary bio-robotic automation for isolation of circulating tumor cell (CTCs). CytoBot™ effectively obviates all manual operations involved in the gradient density separation, negative selection, immuno- and DNA- labeling of CTCs, thereby achieving unprecedented precision, accuracy, and reproducibility required for clinical adoption.

CytoBot™ integrates robotics, sensors and smart software to perform complex biological tasks of CTC isolation. Starting from whole blood in a collection tube, two 6-axial robotic arms simulate a concerted action of centrifuge, pipetting, transferring, shaking, aspirating, washing, labeling, and staining of CTCs. Throughout the process, robotic arms are guided by a multitude of real-time optical, electrical, and mechanical sensors, and intelligent algorithm for high throughput and multi-task functions.

CytoBot™ is supported by a complete CTC isolation kit consisting of monoclonal antibodies, FISH probes, and peripheral bioreagents. Leveraging the principle of negative selection, these reagents do not rely on surface biomarkers for cell isolation. This is a particular advantage in CTC isolation due to protein and genetic biomarker alterations during cell evolution. CytoBot™ is a powerful platform in the growing field of CTCs and their clinical applications.

Catalog # : M0015
Price: Please Inquire
CRC Subtypes

  • Circulating tumor cells (CTCs)
  • Circulating progenitor cells (CPCs)
  • Circulating fetal cells (CFCs)
CytoBot™ Advantages

  • Precision, Accuracy, & Reproducibility
  • High Throughput & Multi-Tasking
  • Minimize Cross Contaminations
  • Negative Selection Cell Isolation
CytoBot™ Integration

  • Total Solution Workstation
  • Two 6 Axial Robotic Arms
  • In Process Controls & Sensors
  • Intelligent Software Algorithm
  • Self-Contained Instruments
  • Clean Environment & HEPA Filter














Hardware General Specifications

Dimensions: 2192 mm(h) x 1900 mm (w) x 1300 mm(d)
[ 1830 mm (d) with cart ]
Weight: 1580 kg
Power: 220 VAC, 50 Hz, 40 A
Operating Temperature: 68°F to 86°F (20°C to 30°C)
Hardware Environmental Specifications

Storage Temperature: -5°F to 158°F (-20°C to 70°C)
Operation Altitude: Up to 2000 m
Operation Environment: For Indoor Use
Operating Humidity: 20% to 90% Relative Humidity, Non-Condensing
Storage Humidity: 20% to 95% Relative Humidity, Non-Condensing
Software Specifications

Scanner Function: Scanning Capability to Read QR Code/Barcode
Status Display: Progress and Fluid Handling
System Clean: Prime and Clean
Report Generation: Print and Export File
Necessary Driver: LabVIEW Run-Time Engine
2014 SP1-(Standard RTE)
NI-VISA Run-Time Engine 5.4
Industrial Personal Computer Specifications

Operating System: Windows 8/7/Vista (32-bit and 64-bit)
Windows XP SP3 (32-bit)
Windows Server 2003 R2 (32-bit)
Windows Server 2008 R2 (64-bit)
Processor: Intel® Core™ i5-4570TE or Equivalent
Memory: 2 GB Minimum (4GB Recommended)
Free Disk Space: 1GB
Interfaces: Gigabit LAN Port * 4
100/10M Lan Port * 2
Digital IO Port * 2
2-Axis port * 2
RS-232 * 8
DVI *1
VGA *1
USB port * 6

CytoBot™ system is the trademark and pending patent of Abnova Corporation.

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