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World's Largest Antibody and Recombinant Protein Manufacturer 
 
 

CONGRATULATIONS!

We are pleased to announce Angie Banez, Roopa Thapar and Elena Frolova as the winners of the November 2008 Join Member Drawing.
There is no requirement to buy, just sign up now and win your 30GB Hard Drives.
Go for the December 2008 Join Member Drawing   
 
Latest News on Cancer Research
 
  Cancer Biomarker
  Annexin A3 in Urine: A Highly Specific Noninvasive Marker for Prostate Cancer Early Detection.
J Urol. 2008 Nov 12. [Epub ahead of print]

Abnova product used: ANXA3 Recombinant Protein (P01)
  Label-Free Cancer Markers Detection by Capacitance Biochip.
Sens. Actuators B: Chem. (2008), doi:10.1016/j.snb.2008.09.050

Abnova product used: SERPINB3 monoclonal antibody (M01), clone 2F5
  Gene-expression profiling in Chinese patients with colon cancer by coupling experimental and bioinformatic genomewide gene-expression analyses: identification and validation of IFITM3 as a biomarker of early colon carcinogenesis.
Cancer. 2008 Jul 15;113(2):266-75.

Abnova product used: IFITM3 monoclonal antibody (M01), clone 4C8-1B10
  Neurobiology
   

3 more papers used TARDBP product for research.
Abnova product used: TARDBP monoclonal antibody (M01), clone 2E2-D3

  Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathol. 2008 Nov 7. [Epub ahead of print]
  Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease.
Brain Res. 2008 Nov 1. [Epub ahead of print]
  Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury.
Brain Research (2008), doi:10.1016/j.brainres.2008.10.021
  New Products
 

In November, Abnova launched 800 full-length proteins, 84 Mab, and 490 MaxPab® antibodies. Find your target and try it today! http://www.abnova.com/products/new_products.asp

   
 
 

800 New Full-length Proteins
Go to total protein list.

(http://www.abnova.com/products/products_list.asp?classid=
AC0000000000&OwnClass=1
)

   
 
 

84 New Monoclonal Antibodies
Go to the total monoclonal antibody list.
(http://www.abnova.com/products/products_list.asp?classid=
AF0000000000&OwnClass=1
)

   
 
 

490 New MaxPab® Antibodies
Go to the total MaxPab® antibody list.
(http://www.abnova.com/products/products_list.asp?classid=
AD0000000000&OwnClass=1
)

New Applications
   

490 Western Blot (Transfected lysate)

 


52 Immunohistochemistry

193 Sandwich ELISA

 

December E-Newsletter

Products News


Purchase any KAxxxx, MABxxxx or PABxxxx and get FREE SHIPPING until December 31st, 2008.


Apoptosis Antibodies
Antibodies detecting
programmed cell death in multicellular organisms.


Ab for Cell Signaling
Antibodies tools for controlling cellular activities and
coordinating cell actions.


Ab for Membrane Proteins
Find your antibodies for
receptors, ion-channels, and transporters.


Modification-State Ab
More antibodies specific for protein modification -
methylation, acetylation and glycosylation
  New Publications
 

Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.
Royer-Zemmour B, Ponsole-Lenfant M, Gara H, Roll P, Leveque C, Massacrier A, Ferracci G, Cillario J, Robaglia-Schlupp A, Vincentelli R, Cau P, Szepetowski P.
Hum Mol Genet. 2008 Dec 1;17(23):3617-30. Epub 2008 Aug 21.
Abnova product used: PLAUR Recombinant Protein (P01)

 

FAM29A promotes microtubule amplification via recruitment of the NEDD1íV{gamma}-tubulin complex to the mitotic spindle.
Zhu H, Coppinger JA, Jang CY, Yates JR, III, Fang J.
J. Cell Biol. (2008), doi/10.1083/jcb.200807046
Abnova product used: NEDD1 monoclonal antibody (M05), clone 7D10

 

5,10-Methenyltetrahydrofolate Synthetase Activity is Increased in Tumors and Modifies the Efficacy of Antipurine LY309887.
Field MS, Anguera MC, Page R, Stover PJ.
Arch. Biochem. Biophys. (2008), doi:10.1016/j.abb.2008.11.001
Abnova product used: GART monoclonal antibody (M01), clone 4D6-1D5

 

Protein disulfide isomerases are antibody targets during immune-mediated tumor destruction.
Fonseca C, Soiffer R, Ho V, Vanneman M, Jinushi M, Ritz J, Neuberg D, Stone R, Deangelo D, Dranoff G.
Blood. 2008 Nov 13. [Epub ahead of print]
Abnova product used: PDIA6 MaxPab polyclonal antibody (B01)

 

Annexin A3 in Urine: A Highly Specific Noninvasive Marker for Prostate Cancer Early Detection.
Schostak M, Schwall GP, Poznanovic? S, Groebe K, Muller M, Messinger D, Miller K, Krause H, Pelzer A, Horninger W, Klocker H, Hennenlotter J, Feyerabend S, Stenzl A, Schrattenholz A.
J Urol. 2008 Nov 12. [Epub ahead of print]
Abnova product used: ANXA3 Recombinant Protein (P01)

 

A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells.
Xu M, McCarrey JR, Hecht NB.
Nucleic Acids Res. 2008 Nov 10. [Epub ahead of print]
Abnova product used: KHSRP polyclonal antibody (A01)

 

Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.
Kasai T, Tokuda T, Ishigami N, Sasayama H, Foulds P, Mitchell DJ, Mann DM, Allsop D, Nakagawa M.
Acta Neuropathol. 2008 Nov 7. [Epub ahead of print]
Abnova product used: TARDBP monoclonal antibody (M01), clone 2E2-D3

 

NDE1, NDEL1: Multimerisation, alternate splicing and DISC1 interaction.
Bradshaw NJ, Christie S, Soares DC, Carlyle BC, Porteous DJ, Millar JK.
Neurosci Lett. 2008 Nov 7. [Epub ahead of print]
Abnova product used: NDE1 monoclonal antibody (M01), clone 2G11-1C11

 

Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis.
Rey MA, Duffy SP, Brown JK, Kennedy JA, Dick JE, Dror Y, Tailor CS.
Haematologica. 2008 Nov;93(11):1617-26. Epub 2008 Sep 24.
Abnova product used: RPS19 monoclonal antibody (M01), clone 3C6

 

Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease.
Seppanen A, Pikkarainen M, Hartikainen P, Hofmann SC, Majamaa K, Alafuzoff I.
Brain Res. 2008 Nov 1. [Epub ahead of print]
Abnova product used: TARDBP monoclonal antibody (M01), clone 2E2-D3

 

Identification of Pbx1, a Potential Oncogene, as a Notch3 Target Gene in Ovarian Cancer.
Park JT, Shih IeM, Wang TL.
Cancer Res. 2008 Nov 1;68(21):8852-60.
Abnova product used: NOTCH3 monoclonal antibody (M01), clone 1G5

 

A large ribonucleoprotein particle induced by cytoplasmic PrP shares striking similarities with the chromatoid body, an RNA granule predicted to function in posttranscriptional gene regulation.
Beaudoin S, Vanderperre B, Grenier C, Tremblay I, Leduc F, Roucou X.
Biochim Biophys Acta. 2008 Oct 30. [Epub ahead of print]
Abnova product used: DCP1A monoclonal antibody (M06), clone 3G4

 

Copper-Induced Translocation of the Wilson Disease Protein ATP7B Independent of Murr1/COMMD1 and Rab7.
Weiss KH, Lozoya JC, Tuma S, Gotthardt D, Reichert J, Ehehalt R, Stremmel W, Fullekrug J.
Am J Pathol. 2008 Dec;173(6):1783-1794. Epub 2008 Oct 30
Abnova product used: COMMD1 monoclonal antibody (M01), clone 2A12

 

EF1A1-Actin interactions alter mRNA stability to determine differential osteopontin expression in HepG2 and Hep3B cells.
Zhang J, Guo H, Mi Z, Gao C, Bhattacharya S, Li J, Kuo PC.
Experimental Cell Research (2008), doi:10.1016/j.yexcr.2008.10.042
Abnova product used: EEF1A1 polyclonal antibody (A01)

 

H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of KATP channels.
Siebert N, Cantre D, Eipel C, Vollmar B.
Am J Physiol Gastrointest Liver Physiol. 2008 Oct 30. [Epub ahead of print]
Abnova product used: CTH monoclonal antibody (M03), clone S51

 

A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice as compared to -217G.
Jain S, Vinukonda G, Fiering SN, Kumar A.
Am J Physiol Regul Integr Comp Physiol. 2008 Oct 22. [Epub ahead of print]
Abnova product used: AGT monoclonal antibody (M01), clone 1A10 and Goat Anti-Mouse IgG (H&L)-Cy3 Conjugate secondary antibody

 

DNAI2 Mutations Cause Primary Ciliary Dyskinesia with Defects in the Outer Dynein Arm.
Loges NT, Olbrich H, Fenske L, Mussaffi H, Horvath J, Fliegauf M, Kuhl H, Baktai G, Peterffy E, Chodhari R, Chung EM, Rutman A, O'Callaghan C, Blau H, Tiszlavicz L, Voelkel K, Witt M, Zi?tkiewicz E, Neesen J, Reinhardt R, Mitchison HM, Omran H.
Am J Hum Genet. 2008 Oct 22. [Epub ahead of print]
Abnova product used: DNAI2 monoclonal antibody (M01), clone 1C8

 

Fetal Exposure to Cocaine Causes Programming of Prkce Gene Repression in the Left Ventricle of Adult Rat Offspring.
Zhang H, Meyer KD, Zhang L.
Biol Reprod. 2008 Oct 22. [Epub ahead of print]
Abnova product used: MTF1 monoclonal antibody (M01), clone 2E5

COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with PtdIns(4,5)p2.
Burkhead JL, Morgan CT, Shinde U, Haddock G, Lutsenko S.
J Biol Chem. 2008 Oct 21. [Epub ahead of print]
Abnova product used: COMMD1 monoclonal antibody (M01), clone 2A12

STIM1 is essential for Fc{gamma} receptor activation and autoimmune inflammation.
Braun A, Gessner JE, Varga-Szabo D, Syed SN, Konrad S, Stegner D, Vogtle T, Schmidt RE, Nieswandt B.
Blood. 2008 Oct 21. [Epub ahead of print]
Abnova product used: STIM1 monoclonal antibody (M01), clone 5A2

Proteomic Analysis of Left Ventricular Remodeling in an Experimental Model of Heart Failure.
Cieniewski-Bernard C, Mulder P, Henry JP, Drobecq H, Dubois E, Pottiez G, Thuillez C, Amouyel P, Richard V, Pinet F.
J Proteome Res. 2008 Nov 7;7(11):5004-5016. Epub 2008 Oct 16.
Abnova product used: ACATE2 monoclonal antibody (M01), clone 4E4

Label-Free Cancer Markers Detection by Capacitance Biochip.
Carrara S, Bhalla V, Stagni C, Benini L, Ferretti A, Valle F, Gallotta A, Ricco? B, Samori B.
Sens. Actuators B: Chem. (2008), doi:10.1016/j.snb.2008.09.050
Abnova product used: SERPINB3 monoclonal antibody (M01), clone 2F5

Genetic screening in C. Elegans identifies rho- GTPase activating protein 6 as novel HERG regulator.
Potet F, Petersen CI, Boutaud O, Shuai W, Stepanovic SZ, Balser JR, Kupershmidt S.
Journal of Molecular and Cellular Cardiology (2008), doi:10.1016/j.yjmcc.2008.10.015
Abnova product used: ARHGAP6 monoclonal antibody (M01), clone 6B3

Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury.
Moisse K, Volkening K, Leystra-Lantz C, Welch I, Hill T, Strong MJ.
Brain Research (2008), doi:10.1016/j.brainres.2008.10.021
Abnova product used: TARDBP monoclonal antibody (M01), clone 2E2-D3

Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes.
Ionova IA, Vasquez-Vivar J, Whitsett J, Herrnreiter A, Medhora M, Cooley BC, Pieper GM.
Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2178-87. Epub 2008 Oct 3.
Abnova product used: DHFR monoclonal antibody (M01), clone 2B10

Ultra-highly sensitive and wash-free bio-detection of H5N1 virus by immunomagnetic reduction assays.
Yang SY, Chieh JJ, Wang WC, Yu CY, Lan CB, Chen JH, Horng HE, Hong CY, Yang HC, Huang W.
J Virol Methods. 2008 Nov;153(2):250-2. Epub 2008 Sep 19.
Abnova product used: H5N1 monoclonal antibody, clone 1B8 and H5N1 monoclonal antibody, clone 4D4

The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population.
Ma Y, Wu L, Liu C, Xu L, Li D, Li JC.
J Cancer Res Clin Oncol. 2008 Sep 11. [Epub ahead of print]
Abnova product used: PINX1 polyclonal antibody (A01)

Megakaryocytic expression of miRNA 10a, 17-5p, 20a and 126 in Philadelphia chromosome-negative myeloproliferative neoplasm.
Hussein K, Dralle W, Theophile K, Kreipe H, Bock O.
Ann Hematol. 2008 Sep 5. [Epub ahead of print]
Abnova product used: RUNX1 monoclonal antibody (M06), clone 2C10

Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development.
Bonnefont J, Nikolaev SI, Perrier AL, Guo S, Cartier L, Sorce S, Laforge T, Aubry L, Khaitovich P, Peschanski M, Antonarakis SE, Krause KH.
Am J Hum Genet. 2008 Aug;83(2):208-18. Epub 2008 Jul 24.
Abnova product used: RFPL1 polyclonal antibody (A01)

Gene-expression profiling in Chinese patients with colon cancer by coupling experimental and bioinformatic genomewide gene-expression analyses: identification and validation of IFITM3 as a biomarker of early colon carcinogenesis.
Fan J, Peng Z, Zhou C, Qiu G, Tang H, Sun Y, Wang X, Li Q, Le X, Xie K.
Cancer. 2008 Jul 15;113(2):266-75.
Abnova product used: IFITM3 monoclonal antibody (M01), clone 4C8-1B10

Immunohistochemical detection of Ndrg2 in the mouse nervous system.
Shen L, Zhao ZY, Wang YZ, Ji SP, Liu XP, Liu XW, Che HL, Lin W, Li X, Zhang J, Yao LB.
Neuroreport. 2008 Jun 11;19(9):927-31.
Abnova product used: NDRG2 monoclonal antibody (M03), clone 6A5

Aptamer-modified monolithic capillary chromatography for protein separation and detection.
Zhao Q, Li XF, Le XC.
Anal Chem. 2008 May 15;80(10):3915-20. Epub 2008 Mar 26.
Abnova product used: Rat liver tissue lysate (non-denatured)

Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.
Smalley DM, Sheman NE, Nelson K, Theodorescu D.
J Proteome Res. 2008 May;7(5):2088-96. Epub 2008 Mar 29.
Abnova product used: EPS8L2 monoclonal antibody (M01), clone 6C2 and MUC4 monoclonal antibody (M07), clone 5B12

Relative quantification of proteins in human cerebrospinal fluids by MS/MS using 6-plex isobaric tags.
Dayon L, Hainard A, Licker V, Turck N, Kuhn K, Hochstrasser DF, Burkhard PR, Sanchez JC.
Anal Chem. 2008 Apr 15;80(8):2921-31. Epub 2008 Mar 1.
Abnova product used: Human S100B ELISA Kit and Human GFAP (Glial Fibrillary Acidic Protein) ELISA

Single-molecular-level study of claudin-1-mediated adhesion.
Lim TS, Vedula SR, Kausalya PJ, Hunziker W, Lim CT.
Langmuir. 2008 Jan 15;24(2):490-5. Epub 2007 Dec 21.
Abnova product used: CLDN1 Recombinant Protein (P01)

Hydroxamic acid derivatives of mycophenolic acid inhibit histone deacetylase at the cellular level.
Batovska DI, Kim DH, Mitsuhashi S, Cho YS, Kwon HJ, Ubukata M.
Biosci Biotechnol Biochem. 2008 Oct;72(10):2623-31. Epub 2008 Oct 7.

IMPDH1 monoclonal antibody (M01), clone 3G6
 
 
Please check Abnova website for regularly updated information.
  Good luck with your research!