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CONGRATULATIONS! September E-Newsletter 
Products News  
   

We are pleased to announce Michael Wilhelm, Donna Saenz and Carolina Arias as
the winners of the August 2008 Join Member Drawing.

  Now, we are offering the opportunity to win an Apple MacBook Air if you place an order online during the month of September.
Give it a try, order today, and enter your drawing for a chance to win!
  Latest News on Cancer Research


Order online today, and enter your drawing for a chance to win!
 
  Gastric Cancer
Prognostic Relevance of Tensin4 Expression in Human Gastric Cancer.
Ann Surg Oncol. 2008 Sep;15(9):2606-13. Epub 2008 Jul 9.
Abnova product used: TNS4 monoclonal antibody (M01), clone 3B8
Clinical Significance of Loss of Fhl1 Expression in Human Gastric Cancer.
Ann Surg Oncol. 2008 Aug;15(8):2293-300. Epub 2008 May 9.
Abnova product used: FHL1 monoclonal antibody (M05), clone 2F7
  Prostate Cancer
A feedback loop between the androgen receptor and a NEDD4 binding protein, PMEPA1 in
prostate cancer cells.
J Biol Chem. 2008 Aug 14. [Epub ahead of print]

Abnova product used: TMEPAI monoclonal antibody (M01), clone 2A1

Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer.
Cancer Res. 2008 Aug 1;68(15):6407-15.

Abnova product used: RDH5 polyclonal antibody (A01) and HSD17B3 polyclonal antibody (A01)

Elevated expression of L-selectin ligand in lymph node-derived human prostate cancer cells correlates with increased tumorigenicity.
Glycoconj J. 2008 Aug 1. [Epub ahead of print]

Abnova product used: C1GALT1 polyclonal antibody (A01)

Genomic Profiling of MicroRNA and Messenger RNA Reveals Deregulated MicroRNA
Expression in Prostate Cancer.
Cancer Res. 2008 Aug 1;68(15):6162-70.
Abnova product used: PTK9 monoclonal antibody (M02), clone 1E2
New Products
In August, Abnova launched 259 full-length proteins, 1442 Partial-length proteins, 301 Mab, 55 Pab and 429 MaxPab® antibody catalogs. Find your target and try it today!
http://www.abnova.com/products/new products.asp
 

259 New Full-length Proteins /1442 New Partial-length Proteins.
Go to total protein's list.

http://www.abnova.com/products/products_list.asp?classid=
AC0000000000& OwnClass=1
 

301 New Monoclonal Antibodies / 55 New Polyclonal Antibodies.
Go to the total monoclonal antibody list.

http://www.abnova.com/products/products_list.asp?classid=
AE0000000000&OwnClass=1
 

429 New MaxPab® Antibodies.
Go to the total MaxPab® antibody list.

http://www.abnova.com/products/products_list.asp?classid=
AD0000000000&OwnClass=1

 

New Applications
 

28   Western Blot (Cell lysate)

254 Immunofluorescence
201 Western Blot (Tissue lysate)

222 Immunohistochemistry

303 Western Blot (Transfected lysate) 89   Dot Blot (Peptide)
http://www.abnova.com/new products/new application.asp


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 New Publications
 

HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- cotransporter 3.
Salin-Cantegrel A, Shekarabi M, Holbert S, Dion P, Rochefort D, Laganière J, Dacal S, Hince P, Karemera L, Gaspar C,
Lapointe JY, Rouleau GA.
Hum Mol Genet. 2008 Sep 1;17(17):2703-11. Epub 2008 Jun 19.
Abnova product used: SLC12A6 polyclonal antibody (A01)

 

Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner.
Hirata H, Tatsumi H, Sokabe M.
J Cell Sci. 2008 Sep 1;121(Pt 17):2795-804. Epub 2008 Aug 5.
Abnova product used:
ZYX monoclonal antibody (M01), clone 2C10-4A7

 

Prognostic Relevance of Tensin4 Expression in Human Gastric Cancer.
Sakashita K, Mimori K, Tanaka F, Kamohara Y, Inoue H, Sawada T, Hirakawa K, Mori M.
Ann Surg Oncol. 2008 Sep;15(9):2606-13. Epub 2008 Jul 9.
Abnova product used: TNS4 monoclonal antibody (M01), clone 3B8

 

The E6 proteins from multiple beta HPV types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation.
Underbrink MP, Howie HL, Bedard KM, Koop JI, Galloway DA.
J Virol. 2008 Aug 20. [Epub ahead of print]
Abnova product used: UBE3A monoclonal antibody (M01), clone 2F6

 

The kinase domain of mitochondrial PINK1 faces the cytoplasm.
Zhou C, Huang Y, Shao Y, May J, Prou D, Perier C, Dauer W, Schon EA, Przedborski S.
Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12022-7. Epub 2008 Aug 7.
Abnova product used: TOMM20 Recombinant Protein (P01)

 

Clinical Significance of Loss of Fhl1 Expression in Human Gastric Cancer.
Sakashita K, Mimori K, Tanaka F, Kamohara Y, Inoue H, Sawada T, Hirakawa K, Mori M.
Ann Surg Oncol. 2008 Aug;15(8):2293-300. Epub 2008 May 9.
Abnova product used: FHL1 monoclonal antibody (M05), clone 2F7

 

A feedback loop between the androgen receptor and a NEDD4 binding protein, PMEPA1 in prostate cancer cells.
Li H, Xu LL, Masuda K, Raymundo E, McLeod DG, Dobi A, Srivastava S.
J Biol Chem. 2008 Aug 14. [Epub ahead of print]
Abnova product used: TMEPAI monoclonal antibody (M01), clone 2A12

 

Induction of a microbicidal protein psoriasin (S100A7), and its stimulatory effects on normal human keratinocytes.
Niyonsaba F, Hattori F, Maeyama K, Ogawa H, Okamoto K.
J Dermatol Sci. 2008 Aug 13. [Epub ahead of print]
Abnova product used: LBP Recombinant Protein (P01)

 

A Cdo–Bnip-2–Cdc42 signaling pathway regulates p38{alpha}/β MAPK activity and myogenic differentiation.
Kang JS, Bae GU, Yi MJ, Yang YJ, Oh JE, Takaesu G, Zhou YT, Low BC, Krauss RS.
J Cell Biol. 2008 Aug 11;182(3):497-507. Epub 2008 Aug 4.
Abnova product used: ARHGAP1 polyclonal antibody (A01)

 

Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis.
Sasaki T, Marcon E, McQuire T, Arai Y, Moens PB, Okada H.
J Cell Biol. 2008 Aug 11;182(3):449-58. Epub 2008 Aug 4.
Abnova product used: HSPA2 monoclonal antibody (M06), clone S51

 

Interplay between Np95 and Eme1 in the DNA damage response.
Mistry H, Gibson L, Yun JW, Sarras H, Tamblyn L, McPherson JP.
Biochem Biophys Res Commun. 2008 Aug 7. [Epub ahead of print]
Abnova product used: UHRF1 monoclonal antibody (M01), clone 3A11

 

Zfp143 regulates Nanog through modulation of Oct4 binding.
Chen X, Fang F, Liou YC, Ng HH.
Stem Cells. 2008 Aug 7. [Epub ahead of print]
Abnova product used: ZNF143 monoclonal antibody (M01), clone 2B4

 

Sprouty2 inhibitory activity on FGF-signaling is modulated by the protein kinase DYRK1A.
Aranda S, Alvarez M, Turró S, Laguna A, de la Luna S.
Mol Cell Biol. 2008 Aug 4. [Epub ahead of print]
Abnova product used: DYRK1A monoclonal antibody (M01), clone 7D10

 

Circadian clock-controlled intestinal expression of the multidrug resistance gene mdr1a in mice.
Murakami Y, Higashi Y, Matsunaga N, Koyanagi S, Ohdo S.
Gastroenterology doi: 10.1053/j.gastro.2008.07.073
Abnova product used: HLF monoclonal antibody (M04), clone M2

 

Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant
Prostate Cancer.

Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, Wood CA, Ettinger SL, Gleave ME, Nelson CC.
Cancer Res. 2008 Aug 1;68(15):6407-15.
Abnova product used: RDH5 polyclonal antibody (A01) and HSD17B3 polyclonal antibody (A01)

 

Elevated expression of L-selectin ligand in lymph node-derived human prostate cancer cells correlates with
increased tumorigenicity.

Radhakrishnan P, Lin MF, Cheng PW.
Glycoconj J. 2008 Aug 1. [Epub ahead of print]Click here to read
Abnova product used: C1GALT1 polyclonal antibody (A01)

 

Genomic Profiling of MicroRNA and Messenger RNA Reveals Deregulated MicroRNA Expression in Prostate Cancer.
Ambs S, Prueitt RL, Yi M, Hudson RS, Howe TM, Petrocca F, Wallace TA, Liu CG, Volinia S, Calin GA, Yfantis HG,
Stephens RM, Croce CM.
Cancer Res. 2008 Aug 1;68(15):6162-70.
Abnova product used: PTK9 monoclonal antibody (M02), clone 1E2

 

miR-126 Regulates Angiogenic Signaling and Vascular Integrity.
Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D.
Dev Cell. 2008 Aug;15(2):272-84.
Abnova product used: EGFL7 monoclonal antibody (M01), clone 2H6

 

Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer.
Petrova DT, Asif AR, Armstrong VW, Dimova I, Toshev S, Yaramov N, Oellerich M, Toncheva D.
Clin Biochem. 2008 Jul 30. [Epub ahead of print]
Abnova product used: TPD52 polyclonal antibody (A01)

 

Apolipoprotein C1 association with Hepatitis C Virus.
Meunier JC, Russell RS, Engle RH, Faulk KN, Purcell RH, Emerson SU.
J Virol. 2008 Jul 30. [Epub ahead of print]
Abnova product used: APOC1 monoclonal antibody (M01), clone 2E2-1A3

 

Overexpression of FMNL2 is closely related to metastasis of colorectal cancer.
Zhu XL, Liang L, Ding YQ.
Int J Colorectal Dis. 2008 Jul 30. [Epub ahead of print]
Abnova product used: FMNL2 monoclonal antibody (M01), clone 2B4

 

A precursor specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum.
Rabu C, Wipf P, Brodsky JL, High S.
J Biol Chem. 2008 Jul 29. [Epub ahead of print]
Abnova product used: ASNA1 monoclonal antibody (M03), clone 2H3

 

A proteomics approach to identify changes in protein profiles in serum of Familial Adenomatous Polyposis patients.
Quaresima B, Crugliano T, Gaspari M, Faniello MC, Cosimo P, Valanzano R, Genuardi M,
Cannataro M, br>Veltri P, Baudi F, Doldo P, Cuda G, Venuta S, Costanzo F.
Cancer Lett. 2008 Jul 28. [Epub ahead of print]
Abnova product used: AHSG monoclonal antibody (M01), clone 5D8

 

Cellular function of neuropathy target esterase in lysophosphatidylcholine action.
Vose SC, Fujioka K, Gulevich AG, Lin AY, Holland NT, Casida JE.
Toxicol Appl Pharmacol. 2008 Jul 25. [Epub ahead of print]
Abnova product used: LYPLA1 polyclonal antibody (A01)

 

ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.
Ushioda R, Hoseki J, Araki K, Jansen G, Thomas DY, Nagata K.
Science. 2008 Jul 25;321(5888):569-72.
Abnova product used: DNAJC10 polyclonal antibody (A01)

 

Rapid exercise-induced changes in PGC-1{alpha} mRNA and protein in human skeletal muscle.
Mathai AS, Bonen A, Benton CR, Robinson DL, Graham TE.
J Appl Physiol. 2008 Jul 24. [Epub ahead of print]
Abnova product used: PPARGC1B polyclonal antibody (A01)

 

The Dynamics of Mammalian P Body Transport, Assembly and Disassembly In Vivo.
Aizer A, Brody Y, Ler LW, Sonenberg N, Singer RH, Shav-Tal Y.
Mol Biol Cell. 2008 Jul 23. [Epub ahead of print]
Abnova product used: DCP1A monoclonal antibody (M06), clone 3G4

 

Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases.
Lin WL, Dickson DW.
Acta Neuropathol. 2008 Aug;116(2):205-13. Epub 2008 Jul 8.
Abnova product used: TARDBP monoclonal antibody (M01), clone 2E2-D3

 

RDJ2 (DNAJA2) chaperones neural G protein signaling pathways.
Rosales-Hernandez A, Beck KE, Zhao X, Braun AP, Braun JE.
Cell Stress Chaperones. 2008 Jul 2. [Epub ahead of print]
Abnova product used: DNAJA2 monoclonal antibody (M01), clone 2A11-F2

 

Identification of the human Nalpha-acetyltransferase complex B (hNatB) - a complex important for cell cycle progression.
Starheim KK, Arnesen T, Gromyko D, Ryningen A, Varhaug JE, Lillehaug J.
Biochem J. 2008 Jun 20. [Epub ahead of print]
Abnova product used: NAT5 monoclonal antibody (M01), clone 2C6

 

The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1.
Sheu JJ, Choi JH, Yildiz I, Tsai FJ, Shaul Y, Wang TL, Shih IeM.
Cancer Res. 2008 Jun 1;68(11):4050-7.
Abnova product used: BAZ1A monoclonal antibody (M01), clone 1F6

 

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, Kirby J, Siddique T, Shaw PJ, Lee VM, Trojanowski JQ.
Ann Neurol. 2007 May;61(5):427-34.
Abnova product used: TARDBP monoclonal antibody (M01), clone 2E2-D3

 

TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease.
Amador-Ortiz C, Lin WL, Ahmed Z, Personett D, Davies P, Duara R, Graff-Radford NR, Hutton ML, Dickson DW.
Ann Neurol. 2007 May;61(5):435-45.
Abnova product used: TARDBP monoclonal antibody (M01), clone 2E2-D3

Please check Abnova website for regularly updated information.
  Good luck with your research!