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- Home > Products > Polyclonal Ab > Human > Membrane > Transporter > SLC10A1 polyclonal antibody
SLC10A1 polyclonal antibody
- カタログ番号 # : PAB12324
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 39,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Phone : +886-2-87511888
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SLC10A1.
- Immunogen:
- A synthetic peptide corresponding to amino acids at N-terminus of human SLC10A1.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 38.1
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- The sequence different from the rat sequence by one amino acid.
- Form:
- Lyophilized
- Purification:
- Affinity purification
- Recommend Usage:
- Western Blot (1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2 ug/mL)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The human Na+-taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechanism.
Eloranta JJ, Jung D, Kullak-Ublick GA.Mol Endocrinol. 2006 Jan;20(1):65-79. Epub 2005 Aug 25.
- 2.
- Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition.
Ho RH, Leake BF, Roberts RL, Lee W, Kim RB.J Biol Chem. 2004 Feb 20;279(8):7213-22. Epub 2003 Dec 2.
- Application Image
- Western Blot (Tissue lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Entrez GeneID:
- 6554
- Gene Name:
- SLC10A1
- Gene Alias:
- NTCP,NTCP1
- Gene Description:
- solute carrier family 10 (sodium/bile acid cotransporter family), member 1
- Omim ID:
- 182396
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization (SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM
- Other Designations:
- growth-inhibiting protein 29,sodium-dependent taurocholate cotransporter,sodium/bile acid cotransporter
