Rabbit polyclonal antibody raised against synthetic peptide of NTRK2.
Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 810 of human NTRK2.
Host:
Rabbit
Theoretical MW (kDa):
140, 110, 80
Reactivity:
Chicken, Human, Mouse, Rat
Specificity:
Trk protein exists as variably glycosylated entities with the major forms having molecular weights of 140 KDa, 110 KDa, and the unglycosylated form of 80 KDa.
Form:
Liquid
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Western Blot (0.5-4 ug/mL) Immunofluorescence (5-10 ug/mL) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
Storage Instruction:
Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Applications
Western Blot (Cell lysate)
Western blot analysis of NTRK2 expression in HL-60 Cell Lysate.
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations:
BDNF/NT-3 growth factors receptor,OTTHUMP00000021573,OTTHUMP00000021574,OTTHUMP00000021575,OTTHUMP00000021576,OTTHUMP00000021577,tyrosine kinase receptor B