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- Home > Products > Polyclonal Ab > Phospho-Specific > HDAC1 (phospho S423) polyclonal antibody
HDAC1 (phospho S423) polyclonal antibody
- カタログ番号 # : PAB4927
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 41,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Phone : +886-2-87511888
Fax : +886-2-87511166- 製品は、お客様に直接出荷されます。
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of HDAC1.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S423 of human HDAC1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Histone deacetylase 1 represses the small GTPase RhoB expression in human nonsmall lung carcinoma cell line.
Wang S, Yan-Neale Y, Fischer D, Zeremski M, Cai R, Zhu J, Asselbergs F, Hampton G, Cohen D.Oncogene. 2003 Sep 18;22(40):6204-13.
- 2.
- Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter.
Di Padova M, Bruno T, De Nicola F, Iezzi S, D'Angelo C, Gallo R, Nicosia D, Corbi N, Biroccio A, Floridi A, Passananti C, Fanciulli M.J Biol Chem. 2003 Sep 19;278(38):36496-504. Epub 2003 Jul 7.
- 3.
- MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein.
Xia ZB, Anderson M, Diaz MO, Zeleznik-Le NJ.Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8342-7. Epub 2003 Jun 26.
- Entrez GeneID:
- 3065
- Protein Accession#:
- Q13547
- Gene Name:
- HDAC1
- Gene Alias:
- DKFZp686H12203,GON-10,HD1,RPD3,RPD3L1
- Gene Description:
- histone deacetylase 1
- Omim ID:
- 601241
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq
- Other Designations:
- OTTHUMP00000008745,reduced potassium dependency, yeast homolog-like 1
