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- Home > Products > Polyclonal Ab > Human > Cell Cycle > MAPK3 polyclonal antibody
MAPK3 polyclonal antibody
- カタログ番号 # : PAB2824
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 39,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Phone : +886-2-87511888
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAPK3.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human MAPK3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells.
Mukherjee S, Huang H, Petkova SB, Albanese C, Pestell RG, Braunstein VL, Christ GJ, Wittner M, Lisanti MP, Berman JW, Weiss LM, Tanowitz HB.Infect Immun. 2004 Sep;72(9):5274-82.
- 2.
- Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells.
Sebkova L, Pellicano A, Monteleone G, Grazioli B, Guarnieri G, Imeneo M, Pallone F, Luzza F.Infect Immun. 2004 Sep;72(9):5019-26.
- 3.
- Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
Munshi HG, Wu YI, Mukhopadhyay S, Ottaviano AJ, Sassano A, Koblinski JE, Platanias LC, Stack MS.J Biol Chem. 2004 Sep 10;279(37):39042-50. Epub 2004 Jul 9.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of MAPK3 polyclonal antibody (Cat # PAB2824) in HepG2 cell line lysates (35 ug/lane). MAPK3 (arrow) was detected using the purified polyclonal antibody.
- Entrez GeneID:
- 5595
- Protein Accession#:
- NP_002737;P27361
- Gene Name:
- MAPK3
- Gene Alias:
- ERK1,HS44KDAP,HUMKER1A,MGC20180,P44ERK1,P44MAPK,PRKM3
- Gene Description:
- mitogen-activated protein kinase 3
- Omim ID:
- 601795
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000174538,OTTHUMP00000174540,extracellular signal-regulated kinase 1,extracellular signal-related kinase 1
- Interactome
- Gene Pathway
- Acute myeloid leukemia
- Adherens junction
- Alzheimer's disease
- Axon guidance
- B cell receptor signaling pathway
- Bladder cancer
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- Dorso-ventral axis formation
- Endometrial cancer
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Gap junction
- Glioma
- GnRH signaling pathway
- Insulin signaling pathway
- Long-term depression
- Long-term potentiation
- MAPK signaling pathway
- Melanogenesis
- Melanoma
- mTOR signaling pathway
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prion diseases
- Prostate cancer
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- T cell receptor signaling pathway
- TGF-beta signaling pathway
- Thyroid cancer
- Toll-like receptor signaling pathway
- Type II diabetes mellitus
- Vascular smooth muscle contraction
- VEGF signaling pathway
