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- Home > Products > Polyclonal Ab > Human > Apoptosis > BAX polyclonal antibody
BAX polyclonal antibody
- カタログ番号 # : PAB19559
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 39,000
- order now, ship in 5 days
-
-
- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166- 製品は、お客様に直接出荷されます。
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic protein of BAX.
- Immunogen:
- Synthetic protein corresponding to human BAX.
- Host:
- Rabbit
- Reactivity:
- Bovine, Human, Mouse, Pig, Rat, Sheep
- Form:
- Lyophilized
- Purification:
- Protein G purification
- Recommend Usage:
- ELISA (1-2 ug/mL)
Western Blot (2-10 ug/mL)
Immunohistochemistry (2-10 ug/mL)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- Lyophilized from PBS.
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Entrez GeneID:
- 581
- Protein Accession#:
- Q07812
- Gene Name:
- BAX
- Gene Alias:
- BCL2L4
- Gene Description:
- BCL2-associated X protein
- Omim ID:
- 600040
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq
- Other Designations:
- apoptosis regulator BAX
- Interactome
- Related Disease
- Adenocarcinoma
- Ataxia Telangiectasia
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Colon cancer
- Colonic Neoplasms
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Genomic Instability
- Head and Neck Neoplasms
- Helicobacter Infections
- Hematologic Diseases
- Hodgkin Disease
- Kidney Failure, Chronic
- Leukemia, chronic myeloid
- Leukemia, Lymphocytic, Chronic
