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- Home > Products > Polyclonal Ab > Human > Binding > Nucleic Acid Binding > SNAI2 polyclonal antibody
SNAI2 polyclonal antibody
- カタログ番号 # : PAB1923
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 39,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Phone : +886-2-87511888
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SNAI2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human SNAI2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha.
Park SH, Cheung LW, Wong AS, Leung PC.Mol Endocrinol. 2008 Sep;22(9):2085-98. Epub 2008 Jun 11.
- 2.
- Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype.
Belguise K, Guo S, Yang S, Rogers AE, Seldin DC, Sherr DH, Sonenshein GE.Cancer Res. 2007 Dec 15;67(24):11742-50.
- 3.
- Beta-catenin activation and epithelial-mesenchymal transition in the pathogenesis of pterygium.
Kato N, Shimmura S, Kawakita T, Miyashita H, Ogawa Y, Yoshida S, Higa K, Okano H, Tsubota K.Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1511-7.
- Applications
- Western Blot (Tissue lysate)
- SNAI2 polyclonal antibody (Cat # PAB1923) is used in Western blot to detect SNAI2 in mouse heart tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with SNAI2 polyclonal antibody (Cat # PAB1923) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 6591
- Protein Accession#:
- NP_003059;O43623
- Gene Name:
- SNAI2
- Gene Alias:
- MGC10182,SLUG,SLUGH1,WS2D
- Gene Description:
- snail homolog 2 (Drosophila)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq
- Other Designations:
- OTTHUMP00000195093,neural crest transcription factor SLUG,slug (chicken homolog), zinc finger protein,slug homolog, zinc finger protein,snail 2
- Gene Pathway
- Related Disease
