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- Home > Products > Polyclonal Ab > Phospho-Specific > CDC2 (phospho T14) polyclonal antibody
CDC2 (phospho T14) polyclonal antibody
- カタログ番号 # : PAB1634
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 41,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDC2.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T14 of human CDC2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase.
Kramer A, Mailand N, Lukas C, Syljuasen RG, Wilkinson CJ, Nigg EA, Bartek J, Lukas J.Nat Cell Biol. 2004 Sep;6(9):884-91. Epub 2004 Aug 15.
- 2.
- Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation.
Dai X, Yamasaki K, Yang L, Sayama K, Shirakata Y, Tokumara S, Yahata Y, Tohyama M, Hashimoto K.J Invest Dermatol. 2004 Jun;122(6):1356-64.
- 3.
- Mitotic phosphorylation of the peripheral Golgi protein Nir2 by Cdk1 provides a docking mechanism for Plk1 and affects cytokinesis completion.
Litvak V, Argov R, Dahan N, Ramachandran S, Amarilio R, Shainskaya A, Lev S.Mol Cell. 2004 May 7;14(3):319-30.
- Entrez GeneID:
- 983
- Protein Accession#:
- NP_001777;P06493
- Gene Name:
- CDC2
- Gene Alias:
- CDC28A,CDK1,DKFZp686L20222,MGC111195
- Gene Description:
- cell division cycle 2, G1 to S and G2 to M
- Omim ID:
- 116940
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019660,cell cycle controller CDC2,cell division control protein 2 homolog,cell division cycle 2 protein,cyclin-dependent kinase 1,p34 protein kinase
- Gene Pathway
