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GSTA1 polyclonal antibody   

  • カタログ番号 # : PAB13601
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  • サイズ
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  • 100 uL
  • JPY ¥ 41,000
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    1. この価格は、 Japanでのみ有効です。国を選択して下さい。
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant GSTA1.
  • Immunogen:
  • Recombinant protein corresponding to human GSTA1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Specificity:
  • Specific for the alpha form (human and rat). Minimal cross-reactivity with the pi form of GST, but does not cross-react with the mu form of GST. Reactive with 0.2 g of recombinant human GST A1-1.
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.5
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2938
  • Gene Name:
  • GSTA1
  • Gene Alias:
  • GST2,GSTA1-1,GTH1,MGC131939
  • Gene Description:
  • glutathione S-transferase alpha 1
  • Gene Summary:
  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq
  • Other Designations:
  • GST, class alpha, 1,GST-epsilon,OTTHUMP00000016611,S-(hydroxyalkyl)glutathione lyase A1,glutathione S-alkyltransferase A1,glutathione S-aryltransferase A1,glutathione S-transferase 2,glutathione S-transferase A1,glutathione S-transferase Ha subunit 1
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