Rabbit polyclonal antibody raised against synthetic peptide of HDAC1.
Immunogen:
A synthetic peptide corresponding to C-terminus of human HDAC1.
Host:
Rabbit
Theoretical MW (kDa):
58
Reactivity:
Human
Form:
Liquid
Purification:
Immunoaffinity purification
Concentration:
Lot specific
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
Storage Instruction:
Store at 4°C.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq