The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤1.0 ng/mL, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Storage Buffer:
Lyophilized from PBS, pH 7.4
Storage Instruction:
Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene