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- Home > Products > Monoclonal Ab > Human > Binding > Nucleic Acid Binding > MCM7 monoclonal antibody, clone DCS-141.1
MCM7 monoclonal antibody, clone DCS-141.1
- カタログ番号 # : MAB9653
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 1 mL
- JPY ¥ 75,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant MCM7.
- Immunogen:
- Recombinant protein corresponding to full length of human MCM7.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Lyophilized
- Isotype:
- IgG1
- Recommend Usage:
- Immunohistochemistry (1:25-1:50)
Western Blot (1:25-1:50)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- Lyophilized from tissue culture supernatant (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C on dry atmosphere.
After reconstitution with steril distilled water, Store at 4°C for at least two months.
For long term storage store at -20°C or below.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 4176
- Gene Name:
- MCM7
- Gene Alias:
- CDABP0042,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS-146
- Gene Description:
- minichromosome maintenance complex component 7
- Omim ID:
- 600592
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- DNA replication licensing factor MCM7,MCM7 minichromosome maintenance deficient 7,homolog of S. cerevisiae Cdc47,minichromosome maintenance deficient 7
- Interactome
- Gene Pathway
- Related Disease
