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- Home > Products > Monoclonal Ab > Human > Signal Transduction > CD8A monoclonal antibody, clone UCHT4
CD8A monoclonal antibody, clone UCHT4
- カタログ番号 # : MAB6898
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 39,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Phone : +886-2-87511888
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD8A.
- Immunogen:
- Native purified CD8A from human thymocytes/Sezary T cells.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2a
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
- Storage Instruction:
- Store at 4°C.
- Publication Reference
- 1.
- Interaction between CD8 and major histocompatibility complex (MHC) class I mediated by multiple contact surfaces that include the alpha 2 and alpha 3 domains of MHC class I.
Sun J, Leahy DJ, Kavathas PB.J Exp Med. 1995 Nov 1;182(5):1275-80.
- 2.
- The CD8 coreceptor revisited: one chain good, two chains better.
Zamoyska R.Immunity. 1994 Jul;1(4):243-6.
- 3.
- Induction of a T-cell mediated suppressor activity by soluble products from antigen-specific helper/inducer human T-cell lines.
Fischer A, Beverley P, Feldmann M, Smith S.Immunology. 1983 Jan;48(1):177-86.
- Application Image
- Immunohistochemistry (Frozen sections)
- Immunoprecipitation
- Flow Cytometry
- Entrez GeneID:
- 925
- Gene Name:
- CD8A
- Gene Alias:
- CD8,Leu2,MAL,p32
- Gene Description:
- CD8a molecule
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD8 antigen alpha polypeptide,CD8 antigen, alpha polypeptide (p32),Leu2 T-lymphocyte antigen,OKT8 T-cell antigen,T cell co-receptor,T-cell antigen Leu2,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2,T8 T-cell ant
