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- Home > Products > Monoclonal Ab > Human > Signal Transduction > BSG monoclonal antibody, clone MEM-M6/6
BSG monoclonal antibody, clone MEM-M6/6
- カタログ番号 # : MAB6448
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 39,000
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against BSG.
- Immunogen:
- Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimmer).
- Host:
- Mouse
- Theoretical MW (kDa):
- 50-60
- Reactivity:
- Human
- Specificity:
- This antibody recognizes Ig domain D2 (membrane proximal) of CD147 (Neurothelin), a 50-60 KDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, 300 mM NaCl, pH 7.4
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Publication Reference
- 1.
- Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes.
Schmidt R, Bultmann A, Fischel S, Gillitzer A, Cullen P, Walch A, Jost P, Ungerer M, Tolley ND, Lindemann S, Gawaz M, Schomig A, May AE.Circ Res. 2008 Feb 15;102(3):302-9. Epub 2007 Nov 29.
- 2.
- Cyclophilin B induces integrin-mediated cell adhesion by a mechanism involving CD98-dependent activation of protein kinase C-delta and p44/42 mitogen-activated protein kinases.
Melchior A, Denys A, Deligny A, Mazurier J, Allain F.Exp Cell Res. 2008 Feb 1;314(3):616-28. Epub 2007 Nov 17.
- 3.
- T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density.
Koch C, Staffler G, Huttinger R, Hilgert I, Prager E, Cerny J, Steinlein P, Majdic O, Horejsi V, Stockinger H.Int Immunol. 1999 May;11(5):777-86.
- Application Image
- Western Blot
- Flow Cytometry
- Entrez GeneID:
- 682
- Gene Name:
- BSG
- Gene Alias:
- 5F7,CD147,EMMPRIN,M6,OK,TCSF
- Gene Description:
- basigin (Ok blood group)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD147 antigen,M6 leukocyte activation antigen,OK blood group antigen,basigin,collagenase stimulatory factor,extracellular matrix metalloproteinase inducer
- Related Disease
