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- Home > Products > Monoclonal Ab > Human > Apoptosis > CD14 monoclonal antibody, clone biG 10
CD14 monoclonal antibody, clone biG 10
- カタログ番号 # : MAB5653
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 39,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Phone : +886-2-87511888
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against CD14.
- Immunogen:
- Monocytes and immunoaffinity purified soluble human CD14.
- Host:
- Mouse
- Reactivity:
- Bovine, Horse, Human, Pig
- Specificity:
- biG 10 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.
- Form:
- Lyophilized
- Isotype:
- IgG1
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Storage Buffer:
- Lyophilized from PBS
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Publication Reference
- 1.
- Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells.
Bruzzone S, De Flora A, Usai C, Graeff R, Lee HC.Biochem J. 2003 Oct 15;375(Pt 2):395-403.
- 2.
- Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression.
Sing A, Rost D, Tvardovskaia N, Roggenkamp A, Wiedemann A, Kirschning CJ, Aepfelbacher M, Heesemann J.J Exp Med. 2002 Oct 21;196(8):1017-24.
- 3.
- Mutation of amino acids 39-44 of human CD14 abrogates binding of lipopolysaccharide and Escherichia coli.
Stelter F, Bernheiden M, Menzel R, Jack RS, Witt S, Fan X, Pfister M, Schutt C.Eur J Biochem. 1997 Jan 15;243(1-2):100-9.
- Application Image
- Western Blot
- ELISA
- Flow Cytometry
- Entrez GeneID:
- 929
- Gene Name:
- CD14
- Gene Alias:
- -
- Gene Description:
- CD14 molecule
- Omim ID:
- 158120
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq
- Other Designations:
- CD14 antigen,monocyte differentiation antigen CD14
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