Mouse monoclonal antibody raised against native CD14.
Immunogen:
Native purified CD14 from human lung Angiotensin Converting Enzyme.
Host:
Mouse
Reactivity:
Human
Specificity:
The monoclonal antibody is directed against the CD14- antigen, which is expressed on human monocytes and macrophages. This antibody reacts with human monocytes and macrophages; weak reactions may occur with neutrophils. 55kD MW monocyte surface antigen identified by monoclonal antibodies belonging to the CD14 cluster and found on peripheral blood monocytes and weakly on granulocytes. Monocytic cells, interfollicular dendritic cells and dendritic reticulum cells are stained in sections of lymphoid tissue sections.
Form:
Liquid
Isotype:
IgG1
Recommend Usage:
Flow Cytometry (20 ul/106 cells) The optimal working dilution should be determined by the end user.
Storage Buffer:
In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
Storage Instruction:
Store in the dark at 4°C. Avoid prolonged exposure to light.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq