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- Home > Products > Monoclonal Ab > Human > Signal Transduction > CD80 monoclonal antibody, clone MAB104
CD80 monoclonal antibody, clone MAB104
- カタログ番号 # : MAB4670
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 200 ug
- JPY ¥ 75,000
- order now, ship in 5 days
-
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Phone : +886-2-87511888
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD80.
- Immunogen:
- Native purified CD80 from Jijoye cells (Human Burkitt Lymphoma cell line).
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- B cell activation antigen B7-1 is also called BB1 and clustered as CD80 during the 5th Leucocyte Typing workshop. CD80 is a member of the Ig superfamily and serves as the ligand for two T-cell molecules, CD28 and CD152 (CTLA-4). Reacts with in vitro activated normal B cells. Reacts weakly with a small proportion of non-activated normal B cells. Does not react with peripheral monocytes, resting and activated normal T cells, T-cell lines and T-cell clones. The molecular weight of the recognized antigen is 60KDa.
- Form:
- Lyophilized
- Isotype:
- IgG1
- Recommend Usage:
- Immunofluorescence (2ug/5x105 cells/test)
Flow Cytometry (2ug/5x105 cells/test)
Immunohistochemistry (Frozen sections)(1:20-1:50)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- Lyophilized from PBS (1mg/mL BSA)
- Storage Instruction:
- Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Publication Reference
- 1.
- IL-4 and IL-2 upregulate the expression of antigen B7, the B cell counterstructure to T cell CD28: an amplification mechanism for T-B cell interactions.
Valle A, Aubry JP, Durand I, Banchereau J.Int Immunol. 1991 Mar;3(3):229-35.
- 2.
- Role of the CD28 receptor in T-cell activation.
June CH, Ledbetter JA, Linsley PS, Thompson CB.Immunol Today. 1990 Jun;11(6):211-6.
- 3.
- mAb 104, a new monoclonal antibody, recognizes the B7 antigen that is expressed on activated B cells and HTLV-1-transformed T cells.
Valle A, Garrone P, Yssel H, Bonnefoy JY, Freedman AS, Freeman G, Nadler LM, Banchereau J.Immunology. 1990 Apr;69(4):531-5.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry (Frozen sections)
- Immunofluorescence
- Flow Cytometry
- Entrez GeneID:
- 941
- Gene Name:
- CD80
- Gene Alias:
- CD28LG,CD28LG1,LAB7
- Gene Description:
- CD80 molecule
- Omim ID:
- 112203
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The B-lymphocyte activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 (MIM 186760) and CTLA4 (MIM 123890) ligands of T cells.[supplied by OMIM
- Other Designations:
- B-lymphocyte activation antigen B7,CD80 antigen,CD80 antigen (CD28 antigen ligand 1, B7-1 antigen),costimulatory factor CD80,costimulatory molecule variant IgV-CD80
- Interactome
- Related Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bronchiolitis, Viral
- Carcinoma, Hepatocellular
- Celiac Disease
- Disease Progression
- Genetic Predisposition to Disease
- Hepatitis C
- Infant, Premature, Diseases
- Liver Neoplasms
- Lung Neoplasms
- Lupus Erythematosus, Systemic
- Multiple Sclerosis
- Papillomavirus Infections
- Pulmonary Disease, Chronic Obstructive
- Respiratory Syncytial Virus Infections
- Sarcoidosis
- Urinary Bladder Neoplasms
