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- Home > Products > Monoclonal Ab > Human > Cell Ad/Junc/Cytoskel > CD34 monoclonal antibody, clone 4H11[APG]
CD34 monoclonal antibody, clone 4H11[APG]
- カタログ番号 # : MAB3835
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 39,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD34.
- Immunogen:
- Native purified CD34 from permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia.
- Host:
- Mouse
- Theoretical MW (kDa):
- 110-115
- Reactivity:
- Human
- Specificity:
- This antibody reacts with Class III epitope on CD34 (Mucosialin), a 110-115 KDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. This antibody completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Recommend Usage:
- Western Blot (2 mg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 mg/mL)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hematopoietic stem cell antigen CD34: role in adhesion or homing.
Gangenahalli GU, Singh VK, Verma YK, Gupta P, Sharma RK, Chandra R, Luthra PM.Stem Cells Dev. 2006 Jun;15(3):305-13.
- 2.
- Three-dimensional structure prediction of the interaction of CD34 with the SH3 domain of Crk-L.
Gangenahalli GU, Singh VK, Verma YK, Gupta P, Sharma RK, Chandra R, Gulati S, Luthra PM.Stem Cells Dev. 2005 Oct;14(5):470-7.
- 3.
- Reversibility of CD34 expression on human hematopoietic stem cells that retain the capacity for secondary reconstitution.
Dao MA, Arevalo J, Nolta JA.Blood. 2003 Jan 1;101(1):112-8. Epub 2002 Jul 25.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Flow Cytometry
- enlarge
- Entrez GeneID:
- 947
- Gene Name:
- CD34
- Gene Alias:
- -
- Gene Description:
- CD34 molecule
- Omim ID:
- 142230
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells.[supplied by OMIM
- Other Designations:
- CD34 antigen,OTTHUMP00000034733,OTTHUMP00000034734,hematopoietic progenitor cell antigen CD34
