Mouse monoclonal antibody raised against recombinant SERPINE1.
Recombinant protein corresponding to human SERPINE1.
This mouse monoclonal antibody is specific to complexed forms of human plasminogen activator inhibitor-1 (PAI-1). This antibody exhibits neoantigenic properties that allow for binding with any complexed form of PAI-1.
The optimal working dilution should be determined by the end user.
In 100 mM HEPES, 100 mM NaCl, 1 mM EDTA, pH 7.4
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
plasminogen activator inhibitor, type I,plasminogen activator inhibitor-1,serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1