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- Home > Products > Monoclonal Ab > Human > Cell Ad/Junc/Cytoskel > CYR61 monoclonal antibody, clone 3H3
CYR61 monoclonal antibody, clone 3H3
- カタログ番号 # : MAB2043
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 uL
- JPY ¥ 39,000
- order now, ship in 5 days
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant CYR61.
- Immunogen:
- Recombinant protein corresponding to amino acids 168-242 of human CYR61.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway.
Tong X, O'Kelly J, Xie D, Mori A, Lemp N, McKenna R, Miller CW, Koeffler HP.Oncogene. 2004 Jun 17;23(28):4847-55.
- 2.
- Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling.
Latinkic BV, Mercurio S, Bennett B, Hirst EM, Xu Q, Lau LF, Mohun TJ, Smith JC.Development. 2003 Jun;130(11):2429-41.
- 3.
- CYR61 stimulates human skin fibroblast migration through Integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its carboxyl-terminal domain.
Grzeszkiewicz TM, Kirschling DJ, Chen N, Lau LF.J Biol Chem. 2001 Jun 15;276(24):21943-50. Epub 2001 Apr 3.
- Entrez GeneID:
- 3491
- Protein Accession#:
- NP_001545
- Gene Name:
- CYR61
- Gene Alias:
- CCN1,GIG1,IGFBP10
- Gene Description:
- cysteine-rich, angiogenic inducer, 61
- Omim ID:
- 602369
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CYR61 is a secreted, cysteine-rich, heparin-binding protein encoded by a growth factor-inducible immediate-early gene. Acting as an extracellular, matrix-associated signaling molecule, CYR61 promotes the adhesion of endothelial cells through interaction with integrin and augments growth factor-induced DNA synthesis in the same cell type.[supplied by OMIM
- Other Designations:
- OTTHUMP00000012303,cysteine-rich heparin-binding protein 61,cysteine-rich, anigogenic inducer, 61
