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- Home > Products > Monoclonal Ab > Human > Binding > Others > TNNI2 monoclonal antibody, clone 2F12A8
TNNI2 monoclonal antibody, clone 2F12A8
- カタログ番号 # : MAB10338
- 頻繁に訪問する :
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- 価格
- 在庫あ
- 入手可能
- カート
- 100 uL
- JPY ¥ 75,000
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Phone : +886-2-87511888
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant TNNI2.
- Immunogen:
- Recombinant protein corresponding to human TNNI2.
- Host:
- Mouse
- Theoretical MW (kDa):
- 21
- Reactivity:
- Human
- Form:
- Liquid
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis using TNNI2 monoclonal antobody, clone 2F12A8 (Cat # MAB10338) against HEK293 (1) and TNNI2-hIgGFc transfected HEK293 (2) cell lysate.
- Western Blot (Recombinant protein)
- Western blot analysis using TNNI2 monoclonal antobody, clone 2F12A8 (Cat # MAB10338) against recombinant human TNNI2 protein.
- Entrez GeneID:
- 7136
- Gene Name:
- TNNI2
- Gene Alias:
- AMCD2B,DA2B,FSSV
- Gene Description:
- troponin I type 2 (skeletal, fast)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000014141,OTTHUMP00000014142,troponin I fast twitch 2,troponin I, fast-twitch skeletal muscle isoform,troponin I, skeletal, fast
- Related Disease
