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Monoclonal Ab
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Transporter
> CCS monoclonal antibody, clone 11G1
CCS monoclonal antibody, clone 11G1
カタログ番号 # : MAB0682
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Specification
Gene Info
Pathway
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Specification
Product Description:
Mouse monoclonal antibody raised against full length recombinant CCS.
Immunogen:
Recombinant protein corresponding to full length human CCS.
Host:
Mouse
Reactivity:
Human
Form:
Liquid
Purification:
Ammonium sulfate precipitation
Concentration:
2 mg/mL
Isotype:
IgG1, kappa
Recommend Usage:
Western Blot (1:180-1:1000)
The optimal working dilution should be determined by the end user.
Storage Buffer:
In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
Storage Instruction:
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Publication Reference
1.
The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis.
Strange RW, Antonyuk S, Hough MA, Doucette PA, Rodriguez JA, Hart PJ, Hayward LJ, Valentine JS, Hasnain SS.J Mol Biol. 2003 May 9;328(4):877-91.
2.
Suppression of manganese superoxide dismutase augments sensitivity to radiation, hyperthermia and doxorubicin in colon cancer cell lines by inducing apoptosis.
Kuninaka S, Ichinose Y, Koja K, Toh Y.Br J Cancer. 2000 Oct;83(7):928-34.
3.
Superoxide dismutase. Organelle specificity.
Weisiger RA, Fridovich I.J Biol Chem. 1973 May 25;248(10):3582-92.
Applications
Western Blot (Cell lysate)
Immunoblot analysis of cell lysates. Lane 1 : Hela cell lysate, lane 2 : 293T cell lysate and lane 3 : Jurkat cell lysate.
ELISA
Application Image
Western Blot (Cell lysate)
enlarge
ELISA
Gene Information
Entrez GeneID:
9973
Gene Name:
CCS
Gene Alias:
MGC138260
Gene Description:
copper chaperone for superoxide dismutase
Omim ID:
603864
Gene Ontology:
Hyperlink
Gene Summary:
Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq
Other Designations:
-
Gene Pathway
Amyotrophic lateral sclerosis (ALS)
Related Disease
Alzheimer Disease
Alzheimer disease
Cognition
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