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- Home > Products > siRNA/Chimera > Pre-design Chimera > Enzyme > Kinase > MET Pre-design Chimera RNAi
MET Pre-design Chimera RNAi
- カタログ番号 # : H00004233-R04
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 10 nmol
- ..........
- 20 nmol
- ..........
-
- This product is not available in Japan.
- お問い合わせ
-
Contact Information
Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166
- Specification
- Product Description:
- Homo sapiens met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000245
- Target Region:
- Coding sequence
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 4233
- Gene Name:
- MET
- Gene Alias:
- AUTS9,HGFR,RCCP2,c-Met
- Gene Description:
- met proto-oncogene (hepatocyte growth factor receptor)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- HGF receptor,OTTHUMP00000069168,SF receptor,met proto-oncogene,met proto-oncogene tyrosine kinase,oncogene MET,scatter factor receptor
- Interactome
- Related Disease
- Adenocarcinoma
- Autistic Disorder
- Carcinoma, Adenosquamous
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Cell Transformation, Neoplastic
- Child Development Disorders, Pervasive
- Chronic Disease
- Cognition Disorders
- Disease Progression
- Gastrointestinal Diseases
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hyperparathyroidism, Secondary
- Lung Neoplasms
- Myopia
- Nasal Polyps
- Neoplasm Metastasis
