Immunoprecipitation of LPL transfected lysate using anti-LPL MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with LPL purified MaxPab mouse polyclonal antibody (B01P) (H00004023-B01P).
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq